Yes I Do
I've been doing it long before the Yarn Harlot...just ask Norma. I always have knitting within reach of the driver's seat. I have stopped knitting and driving somewhat.
You never know when you are going to get stuck in construction....but I actually do most of mine in the car when at long stop lights in Peoria....but before I drive away. I put both hands on the wheel, more for show than anything. Wouldn't want to mess with the other driver's minds.
Or have the state put up some legislation to band knitting while driving.